Home: Table of Contents
Introduction
Scenarios
Bibliography
Chapter 1:
The Ethical Basis of RCRH
The Nature of Science
Research Integrity
Professionalism in Science
Cases
Practical Elements of Responsible Research Conduct
Bibliography
Chapter 2:
Research in Humans
History of Rules About Research in Humans
Definitions
Federal Mandate
Respect for Persons
Beneficence
Justice
Common Rule
Institutional Review Board (IRB) Mission
Cases
Bibliography
Chapter 3:
Ethics and Study Design
Introductory
Ethics Design
Appropriate Risk to Benefit Ratio
Selection of Subject Populations
Cases
Bibliography
Chapter 4:
Conflicts of Interest (COI)
Definitions
Consequences of a COI
Government Intervention
Industry Sponsorship
Professional Societies
Clinical Practice Guidelines
Other Initiatives
COI in Financial Consulting
Cases
Bibliography
Chapter 5:
International Clinical Research
Underlying Conditions
Approval and Monitoring Issues
Study Population Issues
Structural Issues
Epidemiological and Social Science Research
Cases
Bibliography
Chapter 6:
Monitoring Research
Cases
Bibliography
Chapter 7:
Genetics and Stem Cell Research
Genetics
Human Embryonic Stem Cell Research
Bibliography
Chapter 8:
Malfeasance and Misconduct
Definitions
Process
Whistleblowing
Litigation, the New Approach to Research Management
The Importance of Trust
Cases
Bibliography
This product was funded through the Office of Research Integrity, RCR Resource Development Program.
© 2006 University of California Regents. All rights reserved.
