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Consequences of a COI

When an individual COI exists, then independent of the behavior of the investigator, those knowledgeable about the study must take the COI into account when judging the validity of the study.

Beyond that, in clinical research, the well being of the subjects may also be compromised by a COI and this has become an overarching factor in the regulation of financial COIs in clinical research. As noted above, the well being of the participants is paramount and trumps the completion of the research.
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Chapter 4
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Conflicts of Interest (COI)

Definitions

Consequences of a COI

Government Intervention

Industry Sponsorship

Professional Societies

Clinical Practice Guidelines

Other Initiatives

COI in Financial Consulting

Cases

Bibliography


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