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Consequences of a COI
When an individual COI exists, then independent of the behavior of the investigator, those knowledgeable about the study must take the COI into account when judging the validity of the study.
Beyond that, in clinical research, the well being of the subjects may also be compromised by a COI and this has become an overarching factor in the regulation of financial COIs in clinical research. As noted above, the well being of the participants is paramount and trumps the completion of the research.
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Chapter 4
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Conflicts of Interest (COI)
Definitions
Consequences of a COI
Government Intervention
Industry Sponsorship
Professional Societies
Clinical Practice Guidelines
Other Initiatives
COI in Financial Consulting
Cases
Bibliography
Chapter 4 Download (PDF)
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