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Underlying conditions
  1. Governments are less stable, insurgency may impair studies

  2. Protections for citizens are weak

  3. Disease portfolio, nutritional state, health care belief systems are different in developing countries and these differ from locale to locale

  4. Very rudimentary health care systems making it unlikely that study drugs will be affordable by the general population

  5. Serious logistical problems sometimes encountered in carrying out research, power, transportation, communication.

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Chapter 6
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International Clinical Research

Underlying Conditions

Approval and Monitoring Issues

Study Population Issues

Structural Issues

Epidemiological and Social Science Research

Cases

Bibliography


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