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Case: Research with Indigenous Tribe

Deep in the Brazilian jungle the Ogura tribe retains its ancient culture of nakedness, hunting, including the cannibalization of males from other villages and capturing females and children, as well as gathering edible vegetation and fishing in adjacent streams. The Ogura are big and strapping and seem to have a lot of children. However, very few Ogura can be found who appear older than around 50 years of age.

The Brazilian government has made extensive contact with indigenous cultures and has agents and translators who visit regularly and are accepted by the tribe. The government is concerned that tree poachers are destroying the jungle habitat for indigenous cultures. The Ogura, using lightning raids, have killed a number of poachers and, to date, have preserved their environment.

You, as a great public health and genetic researcher have been invited by the government to initiate genetic, anthropological and public health research into the tribe in hopes of helping them survive, either in their own environment or in the modern world.

You see this as a great but ethically challenging opportunity. You schedule a visit to the Ogura with the agent and translator.

Questions:
  1. What issues would you like to cover in your visit?
  2. The desired information includes the blood of as many members of the tribe as possible to do genome analysis and determine whether there are clinical reasons for their apparent short life spans. What ethical issues arise as you consider how to do this?
  3. How will you go about conducting research on this population?

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Chapter 6
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International Clinical Research

Underlying Conditions

Approval and Monitoring Issues

Study Population Issues

Structural Issues

Epidemiological and Social Science Research

Cases

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