Public Health Service

ORI Introduction to RCR: Chapter 4. The Welfare of Laboratory Animals

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US Government Principles for the Utilization and Care
of Vertebrate Animals Use in Testing, Research and Training
[Researchers should:]
  1. follow the rules and regulations for the transportation, care, and use of animals;
  2. design and perform research with consideration of relevance to human or animal health, the advancement of knowledge, or the good of society;
  3. use appropriate species, quality, and the minimum number of animals to obtain valid results, and consider non-animal models;
  4. avoid or minimize pain, discomfort, and distress when consistent with sound scientific practices;
  5. use appropriate sedation, analgesia, or anesthesia;
  6. painlessly kill animals that will suffer severe or chronic pain or distress that cannot be relieved;
  7. feed and house animals appropriately and provide veterinary care as indicated;
  8. assure that everyone who is responsible for the care and treatment of animals during the research is appropriately qualified and trained; and
  9. defer any exceptions to these principles to the appropriate IACUC. (Link

Source URL: https://ori.hhs.gov/content/Chapter-4-The-Welfare-of-Laboratory-Animals-public-health-service