ORI conducts intramural and extramural research programs to expand the knowledge base on research misconduct, research integrity, the responsible conduct of research, and regulatory compliance. Intramural studies are conducted by ORI staff, contractors, and researchers interested in analyzing data available in ORI. The extramural program operates through the Research on Research Integrity (RRI) Program that solicits investigator-initiated proposals from researchers at colleges, universities, medical schools, research centers and other organizations.