Which one of the following statements is NOT true?

Activities involving pathogenic microorganisms and infectious
      agents must be approved by the IBC prior to initiation.
Individuals conducting activities involving biohazards are required
      to participate in appropriate training.
Research involving recombinant DNA must be registered with and,       if required, approved by the IBC prior to commencing.
Importation and interstate shipment of biological materials are
      not regulated.
All of the above are true