Truth is the beginning of every good thing... and he who would be blessed and happy should be from the first a partaker of the truth, for then he can be trusted. – Plato

It seems paradoxical that scientific research, in many ways one of the most questioning and skeptical of human activities, should be dependent on personal trust. But the fact is that without trust the research enterprise could not function. – Arnold Relman
Chapter 4: Discussion and Reflection Questions
1. What issues and concerns did you immediately react to – intellectually and emotionally – in this chapter?
2. What were Nick’s responsibilities for insuring that the research protocol submitted to and approved by the IRB was followed correctly and completely? In what ways did Nick fail to fulfill his responsibilities?
3. Who is at risk when Nick’s research is not compliant with IRB guidelines?
4. What are the risks to each of these individuals or groups?
Research Ethics
Chapter 4: The Devil is in the Details
Discussion and Reflection Questions
Integration Questions
References and Resources

This chapter addresses research with human subjects, including risks, protections, and policies governing responsible research conduct. Research with animals is also discussed. Upon completion of this chapter we hope that you can identify the ethical issues and complexities in research with humans and animals. We want you to learn about the rules, guidelines, and behaviors associated with responsible research.

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