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South African University Finds Research Misconduct

Volume 8, No. 3, June 2000

South Africa joined the growing list of nations that have investigated allegations of scientific misconduct earlier this year when a researcher was accused of falsifying a study of an aggressive treatment for advanced breast cancer involving ultrahigh doses of chemotherapy followed by a bone marrow transplant.

The University of Witwatersrand in Johannesburg fired Professor Werner Bezwoda, chairman, department of oncology and hematology, following a 6-week probe that concluded that he misrepresented his findings and had failed to obtain approval for the trial before proceeding, according to press reports.

The misconduct was discovered when a U.S. delegation of researchers was sent to South Africa to assess Bezwoda's techniques in preparation for replicating his work because he had reported positive results for the high dose treatment while two large U.S. trials found no benefit. The researchers were only able to find records for 50 of the 150 subjects, and those records did not support the reported results, according to press reports.


 
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